October 29, 2020

The Mysterious Power Of Hagfish Slime—Supreme Survival Capacity

At first glance, the hagfish—a sinuous, tubular animal with pink-grey skin and a paddle-shaped tail—looks very much like an eel. Naturalists can tell the two apart because hagfish, unlike other fish, lack backbones (and, also, jaws). For everyone else, there’s an even easier method. “Look at the hand holding the fish,” the marine biologist Andrew Thaler once noted. “Is it completely covered in slime? Then, it’s a hagfish.”

Hagfish produce slime the way humans produce opinions—readily, swiftly, defensively, and prodigiously. They slime when attacked or simply when stressed. On July 14, 2017, a truck full of hagfish overturned on an Oregon highway. The animals were destined for South Korea, where they are eaten as a delicacy, but instead, they were strewn across a stretch of Highway 101, covering the road (and at least one unfortunate car) in slime.

Facebook | Oregon State Police

Facebook | Oregon State Police

Facebook | Oregon State Police

Typically, a hagfish will release less than a teaspoon of gunk from the 100 or so slime glands that line its flanks. And in less than half a second, that little amount will expand by 10,000 times—enough to fill a sizable bucket. Reach in, and every move of your hand will drag the water with it. “It doesn’t feel like much at first, as if a spider has built a web underwater,” says Douglas Fudge of Chapman University. But try to lift your hand out, and it’s as if the bucket’s contents are now attached to you.

Wikipedia

The slime looks revolting, but it’s also one of nature’s more wondrous substances, unlike anything else that’s been concocted by either evolution or engineers. Fudge, who has been studying its properties for two decades, says that when people first touch it, they are invariably surprised. “It looks like a bunch of mucus that someone just sneezed out of their nose,” he says. “That’s not at all what it’s like.”

Wikipedia | Linda Snook

For a start, it’s not sticky. If there wasn’t so damn much of it, you’d be able to wipe it off your skin with ease. The hagfish themselves scrape the slime off their skin by tying a knot in their bodies and sliding it from head to tail.

The slime also “has a very strange sensation of not quite being there,” says Fudge. It consists of two main components—mucus and protein threads. The threads spread out and entangle one another, creating a fast-expanding net that traps both mucus and water. Astonishingly, to create a liter of slime, a hagfish has to release only 40 milligrams of mucus and protein—1,000 times less dry material than human saliva contains. That’s why the slime, though strong and elastic enough to coat a hand, feels so incorporeal.

Wikimedia Commons

Indeed, it’s one of the softest materials ever measured. “Jell-O is between 10,000 and 100,000 times stiffer than hagfish slime,” says Randy Ewoldt from the University of Illinois at Urbana-Champaign, who had to invent new methods for assessing the substance’s properties after conventional instruments failed to cope with its nature. “When you see it in a bucket, it almost still looks like water. Only when you stick your hand in and pick it up do you find that it’s a coherent thing.”

Flickr | hoesim

The proteins threads that give the slime cohesion are incredible in their own right. Each is one-100th the width of a human hair but can stretch for four to six inches. And within the slime glands, each thread is coiled like a ball of yarn within its own tiny cell—a feat akin to stuffing a kilometer of Christmas lights into a shoebox without a single knot or tangle. No one knows how the hagfish achieves this miracle of packaging, but Fudge just got a grant to test one idea. He thinks that the thread cells use their nuclei—the DNA-containing structures at their core—like a spindle, turning them to wind the growing protein threads into a single continuous loop.

Wikimedia Commons

They’re not just slimy…they’re also delicious.

No amount of slime can protect hagfish from fishermen. They’re eaten in some cuisines, particularly in South Korea, as a delicacy. I’ve never eaten hagfish, but they’re similar to eels, so can’t be that bad.

Flickr | dirtsailor2003

Once these cells are expelled from the slime glands, they rupture, releasing the threads within them. Ewoldt’s colleague Gaurav Chaudhury found that despite their length, the threads can fully unspool in a fraction of a second. The pull of flowing water is enough to unwind them. But the process is even quicker if the loose end snags on a surface, like another thread, or a predator’s mouth.

Being extremely soft, the slime is very good at filling crevices, and scientists had long assumed that hagfish use it to clog the gills of would-be predators. That hypothesis was only confirmed in 2011 when Vincent Zintzen from the Museum of New Zealand Te Papa Tongarewa finally captured footage of hagfish sliming conger eels, wreckfish, and more. Even a shark was forced to retreat, visibly gagging on the cloud of slime in its jaws.

That ability makes hagfish not only hard to bite, but also hard to defend against.

Their signature slime might have also evolved as a result of that lifestyle, as a way of fending off predators that were competing for cadavers. “Everything about hagfish is weird,” says Fudge, “but it all kind of fits.”